Rapid onset sensorineural hearing loss secondary to bilateral cerebral melanoma metastases to the cerebellopontine angle.
Rhona Sproat, Mahmood Bhutta, Neil Rane, Pablo Martinez-Devesa
(ENT department, Wexham Park Hospital, Slough, United Kingdom)
JHS 2014; 4(1): CS41-46
We describe a case of bilateral cerebellopontine angle melanoma metastases in the context of a literature review. The case is a rare presentation of sensorineural hearing loss and an unusual site of metastasis for malignant melanoma.
Case Report: A 54-year-old man presented with sudden deafness. Bilateral melanoma metastases were confirmed with MRI and lumbar puncture. He died 3 months after treatment.
Conclusions: Melanoma metastasis should be considered as a differential for sensorineural hearing loss. A review of the literature found that the median survival of patients with bilateral cerebellopontine angle metastatic melanoma is 6 months post-treatment. At surgery these tumours are largely unresectable from cranial nerves VII and VIII. Surgical intervention is unlikely to result in survival or symptomatic benefit and the focus of treatment should be on maintaining quality of life. Hearing rehabilitation and gamma knife surgery may have a role.
Keywords: Cerebellopontine, Hearing, Melanoma