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ORIGINAL ARTICLE
ELECTROPHYSIOLOGICAL MEASURES OF AUDITORY IMPAIRMENT IN NOISE-EXPOSED, NORMAL-HEARING SOLDIERS
1
ENT Department, Yerevan State Medical University, Nairi Medical Center, Yerevan, Armenia
2
Pediatric Otolaryngology and Head and Neck Surgery, Necker–Enfants Malades Hospital, Paris, France
3
ENT Department, Erebouni Medical Center, Yerevan, Armenia
4
ENT Department, Yerevan State Medical University, Astghik Medical Center, Yerevan, Armenia
5
ENT and Maxilofacial Surgery Department, Heratsi Hospital Complex, Yerevan State Medical University, Yerevan, Armenia
6
ENT Department, Yerevan State Medical University, Yerevan, Armenia
A - Research concept and design; B - Collection and/or assembly of data; C - Data analysis and interpretation; D - Writing the article; E - Critical revision of the article; F - Final approval of article;
Submission date: 2024-01-18
Final revision date: 2024-06-04
Acceptance date: 2024-06-20
Online publication date: 2024-08-01
Publication date: 2024-08-01
Corresponding author
J Hear Sci 2024;14(2):39-45
KEYWORDS
TOPICS
ABSTRACT
Introduction:
Some electrophysiological changes can occur in the auditory system in response to noise exposure with or without any permanent auditory threshold shift. The purpose of this study was to identify and measure cochlear function after noise exposure in individuals with normal hearing according to standard audiometric thresholds.
Material and methods:
Pure tone audiometry (PTA) over the standard 0.250–8 kHz range and at 12 kHz, as well as distortion product otoacoustic emission (DPOAE) and auditory brainstem response (ABR) testing, were performed on 42 soldiers who had participated in combat. A control group of 40 participants underwent the same tests.
Results:
In the noise-exposed group, significantly poorer PTA thresholds were recorded at 12 kHz. DPOAE levels were significantly low only at 4 kHz. On ABR testing, both wave I and wave V demonstrated a significant decrease in amplitude and a significant increase in latency for the noise-exposed group.
Conclusions:
Our findings reveal that high levels of noise can not only damage outer hair cells but also cause changes at the level of the synapses (synaptopathy) which are not evident using standard PTA tests. However, electrophysiological methods can detect some changes in cochlear function.
Some electrophysiological changes can occur in the auditory system in response to noise exposure with or without any permanent auditory threshold shift. The purpose of this study was to identify and measure cochlear function after noise exposure in individuals with normal hearing according to standard audiometric thresholds.
Material and methods:
Pure tone audiometry (PTA) over the standard 0.250–8 kHz range and at 12 kHz, as well as distortion product otoacoustic emission (DPOAE) and auditory brainstem response (ABR) testing, were performed on 42 soldiers who had participated in combat. A control group of 40 participants underwent the same tests.
Results:
In the noise-exposed group, significantly poorer PTA thresholds were recorded at 12 kHz. DPOAE levels were significantly low only at 4 kHz. On ABR testing, both wave I and wave V demonstrated a significant decrease in amplitude and a significant increase in latency for the noise-exposed group.
Conclusions:
Our findings reveal that high levels of noise can not only damage outer hair cells but also cause changes at the level of the synapses (synaptopathy) which are not evident using standard PTA tests. However, electrophysiological methods can detect some changes in cochlear function.
REFERENCES (38)
1.
Bramhall NF, Konrad-Martin D, McMillan GP, Griest SE. Auditory brainstem response altered in humans with noise exposure despite normal outer hair cell function. Ear Hear, 2017; 38(1): e1–e12. https://doi.org/10.1097/AUD.00....
2.
Kujawa SG, Liberman MC. Synaptopathy in the noise-exposed and aging cochlea: primary neural degeneration in acquired sensorineural hearing loss. Hear Res, 2015; 330(Pt B): 191–9. https://doi.org/10.1016/j.hear....
3.
Stamper GC, Johnson TA. Auditory function in normal-hearing, noise-exposed human ears. Ear Hear, 2015; 36(2): 172–84. https://doi.org/10.1097/AUD.00....
4.
Attias J, Horovitz G, El-Hatib N, Nageris B. Detection and clinical diagnosis of noise-induced hearing loss by otoacoustic emissions. Noise Health, 2001; 3: 19–31.
5.
Lapsley Miller JA, Marshall L, Heller LM, Hughes LM. Low-level otoacoustic emissions may predict susceptibility to noise-induced hearing loss. J Acoust Soc Am, 2006; 120: 280–96. https://doi.org/10.1121/1.2204....
6.
Marshall L, Lapsley Miller JA, Heller LM, Wolgemuth KS, Hughes LM, et al. Detecting incipient inner-ear damage from impulse noise with otoacoustic emissions. J Acoust Soc Am, 2009; 125: 995–1013. https://doi.org/10.1121/1.3050....
7.
Seixas NS, Neitzel R, Stover B, Sheppard L, Feeney P, Mills D, et al. 10-year prospective study of noise exposure and hearing damage among construction workers. Occup Environ Med, 2012; 69: 643–50. https://doi.org/10.1136/oemed-....
8.
Tepe V, Smalt C, Nelson J, Quatieri T, Pitts K. Hidden hearing injury: the emerging science and military relevance of cochlear synaptopathy. Mil Med, 2017; 182(9): e1785–e1795. https://doi.org/10.7205/milmed....
9.
Jedrzejczak WW, Pilka E, Pastucha M, Kochanek K, Skarzynski H. Extended high frequency thresholds and their relationship to distortion product otoacoustic emissions, hearing acuity, age, gender, presence of spontaneous otoacoustic emissions, and side of measurement. Appl Sciences, 2023; 13(18): 10311. https://doi.org/10.3390/app131....
10.
Laffoon SM, Stewart M, Zheng Y, Meinke DK. Conventional audiometry, extended high-frequency audiometry, and DPOAEs in youth recreational firearm users. Int J Audiol, 2019; 58(Suppl. 1): S40–S48. https://doi.org/10.1080/149920....
11.
International Bureau for Audiophonology, BIAP Recommendation 02/1: Audiometric Classification of Hearing Impairments, https://www.biap.org/en/recomm... [Accessed 9.07.2024].
12.
Jerger J. Clinical experience with impedance audiometry. Arch Otolaryngol, 1970; 92: 311–24.
13.
Baraldi Knobel KA, Ganz Sanchez T. [Loudness discomfort level in normal hearing individuals]. Pro Fono, 2006; 18(1): 31–40 [in Portuguese]. https://doi.org/10.1590/S0104-....
14.
LaGuinn PS, Formby C. Estimates of loudness, loudness discomfort, and the auditory dynamic range: normative estimates, comparison of procedures, and test–retest reliability. J Am Acad Audiol, 2005; 16(2): 85–100. https://doi.org/10.3766/jaaa.1....
15.
International Organization for Standardization. Acoustics – Statistical distribution of hearing thresholds related to age and gender. Geneva: International Organization for Standardization; 2017. ISO 7029: 2017; pp. 1–22.
16.
Jin I-K, Lee D, Jeong Y, Seo YJ, Kong TH, Suh MJ, et al. Trends in distributions of hearing threshold levels by ages: a comparison of the ISO 7029 and newly available country-specific data. J Audiol Otol, 2024; 28(1): 1–9. https://doi.org/10.7874/jao.20....
17.
Lonsbury-Martin BL, McCoy MJ, Whitehead ML, Martin GK. Clinical testing of distortion-product otoacoustic emissions. Ear Hear, 1993; 14(1): 11–22. https://10.1097/00003446-19930....
18.
Kujawa SG, Liberman MC. Adding insult to injury: cochlear nerve degeneration after “temporary” noise-induced hearing loss. J Neurosci, 2009; 29: 14077–85. https://doi.org/10.1523/jneuro....
19.
Lin HW, Furman AC, Kujawa SG, Liberman MCh. Primary neural degeneration in the guinea pig cochlea after reversible noise-induced threshold shift. J Assoc Res Otolaryngol, 2011; 12: 605–16. https://doi.org/10.1007/s10162....
20.
Furman AC, Kujawa SG, Liberman MC. Noise-induced cochlear neuropathy is selective for fibers with low spontaneous rates. J Neurophysiol, 2013; 110: 577–86. https://doi.org/10.1152/jn.001....
21.
Sergeyenko Y, Lall K, Liberman MC, Kujawa SG. Age-related cochlear synaptopathy: an early-onset contributor to auditory functional decline. J Neurosci, 2013; 33: 13686–94. https://doi.org/10.1523/jneuro....
22.
Bhatt IS, Lichtenhan J, Tyler R, Goodman S. Influence of tinnitus, lifetime noise exposure, and firearm use on hearing thresholds, distortion product otoacoustic emissions, and their relative metric. J Acoust Soc Am, 2023; 154, 418–32. https://doi.org/10.1121/10.001....
23.
Nadon V, Bockstael A, Botteldooren D, Voix J. Field monitoring of otoacoustic emissions during noise exposure: pilot study in controlled environment. Am J Audiol, 2017; 26(3S): 352–68. https://doi.org/10.1044/2017_A....
24.
Trzaskowski B, Jędrzejczak WW, Piłka E, Cieślicka M, Skarzynski H. Otoacoustic emissions before and after listening to music on a personal player. Med Sci Monit, 2014; 20: 1426–31. https://doi.org/10.12659/MSM.8....
25.
Kuronen P, Sorri MJ, Pääkkönen R, Muhli A. Temporary threshold shift in military pilots measured using conventional and extended high-frequency audiometry after one flight. Int J Audiol, 2003; 42(1): 29–33. https://doi.org/10.3109/149920....
26.
Kuo CY, Hung CL, Chen HC, Shih CP, Lu RH, Chen CW, et al. The immediate and long-term impact of military aircraft noise on hearing: a cross-sectional comparison of fighter pilots and ground staff. Int J Environ Res Public Health, 2021; 18(6): 2982. https://doi.org/10.3390/ijerph....
27.
Konopka W, Pawlaczyk-Luszczynska M, Sliwinska-Kowalska M, Grzanka A, Zalewski P. Effects of impulse noise on transiently evoked otoacoustic emission in soldiers. Int J Audiol, 2005; 44(1): 3–7. https://doi.org/10.1080/149920....
28.
Fausti SA, Erickson DA, Frey RH, Rappaport BZ, Schechter MA. The effects of noise upon human hearing sensitivity from 8000 to 20 000 Hz. J Acoust Soc Am, 1981; 69(5): 1343–47. https://doi.org/10.1121/1.3858....
29.
Balatsouras DG, Homsioglou E, Danielidis V. Extended high-frequency audiometry in patients with acoustic trauma. Clin Otolaryngol, 2005; 30(3): 249. https://doi.org/10.1111/j.1365....
30.
Ma F, Gong S, Liu S, Hu M, Qin C, Bai Y. Extended high-frequency audiometry (9–20 kHz) in civilian pilots. Aerosp Med Hum Perform, 2018; 89(7): 593–600. https://doi.org/10.3357/AMHP.5....
31.
Büchler M, Kompis M, Hotz MA. Extended frequency range hearing thresholds and otoacoustic emissions in acute acoustic trauma. Otol Neurotol, 2012; 33(8): 1315–22. https://doi.org/10.1097/MAO.0b....
32.
Coats AC, Martin JL. Human auditory nerve action potentials and brain stem evoked responses: effects of audiogram shape and lesion location. Arch Otolaryngol, 1977; 103(10): 605–22. https://doi.org/10.1001/archot....
33.
Gabr TA. Auditory brainstem response audiometry in tinnitus patients. Egypt J Ear Nose Throat Allied Sci, 2011; 12(2): 115–20. 34. Schaette R, McAlpine D. Tinnitus with a normal audiogram: physiological evidence for hidden hearing loss and computational model. J Neurosci, 2011; 31(38): 13452–7. https://doi.org/10.1523/jneuro....
34.
Kaf WA, Turntine M, Jamos A, Smurzynski J. Examining the profile of noise-induced cochlear synaptopathy using iPhone health app data and cochlear and brainstem electrophysiological responses to fast clicks rates. Semin Hear, 2022; 43(3): 197–222. https://doi.org/10.1055/s-0042....
35.
Suresh CH, Krishnan A. Search for electrophysiological indices of hidden hearing loss in humans: click auditory brainstem response across sound levels and in background noise. Ear Hear, 2021; 42(1): 53–67. https://doi.org/10.1097/AUD.00....
36.
Liberman MC, Epstein MJ, Cleveland SS, Wang H, Maison SF. Toward a differential diagnosis of hidden hearing loss in humans. PLoS One, 2016; 11(9): e0162726. https://doi.org/10.1371/journa....
37.
Sheldrake J, Diehl PU, Schaette R. Audiometric characteristics of hyperacusis patients. Front Neurol, 2015; 6: 105. https://doi.org/10.3389/fneur.....
38.
Zaugg TL, Thielman EJ, Griest S, Henry JA. Subjective reports of trouble tolerating sound in daily life versus loudness discomfort levels. Am J Audiol, 2016; 25: 359–63. https://doi.org/10.1044/2016_A....
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