Current Issue
Volumes and Issues
For Authors
Manuscript Guidelines
Review Process
Conflict of Interest
Copyright
About the Journal
Editorial Board
Aim and Scope
Policy and Ethical Guidelines
Promotion of the Journal
Print-Version Subscription
Publisher and Contact Information
Contact Information
Sign in as an AUTHOR/REVIEWER
ORIGINAL ARTICLE
FACTORS INCREASING THE RISK OF HEARING LOSS AMONG HYPERTENSIVE PATIENTS: A PROSPECTIVE STUDY
1
Public Health, Istanbul University Cerrahpasa, Turkey
2
Faculty of Medicine, Istanbul Medipol University, Turkey
3
Biostatistics, Kastamonu University, Turkey
A - Research concept and design; B - Collection and/or assembly of data; C - Data analysis and interpretation; D - Writing the article; E - Critical revision of the article; F - Final approval of article;
Submission date: 2021-11-17
Final revision date: 2022-07-18
Acceptance date: 2022-07-22
Publication date: 2022-09-30
Corresponding author
J Hear Sci 2022;12(3):41-46
KEYWORDS
TOPICS
ABSTRACT
Background:
Hearing loss and hypertension are leading causes of disability, affecting over 360 million people. The aim of this study was to assess the impacts of factors such as vitamin D and sleep disorder on the risk of hearing loss among hypertensive patients.
Material and methods:
This prospective cohort study involved 885 patients aged between 25 and 65 years old who visited our ENT and Endocrinology departments. The study was based on biochemical tests, physical examination, hearing assessment, and Pittsburgh Sleep Quality Index test. Statistical analysis used bivariate and multivariate stepwise regression.
Results:
Of 855 hypertensive patients, 184 (21.5%) had hearing loss. There were statistically significant differences between hypertensive patients with and without hearing loss in terms of BMI, smoking, family history of diabetes, tinnitus, vertigo, and headache. Moreover, there were statistically significant differences between hypertensive patients with hearing loss versus those with normal hearing in terms of vitamin D, calcium, magnesium, potassium, fasting glucose, HbA1C, HDL, systolic and diastolic blood pressure, microalbuminuria, and sleep quality. Among hypertensive patients, a multivariate regression analysis (stepwise method) indicated that vertigo, systolic blood pressure, vitamin D deficiency, numbness in the hand, tinnitus, vigorous activity, metabolic syndrome, sleep disturbance, and obesity were all risk predictors of hearing loss.
Conclusions:
Controlling hypertension, vitamin D level, sleep, and lifestyle might lower the risk of hearing loss among hypertensive patients.
Hearing loss and hypertension are leading causes of disability, affecting over 360 million people. The aim of this study was to assess the impacts of factors such as vitamin D and sleep disorder on the risk of hearing loss among hypertensive patients.
Material and methods:
This prospective cohort study involved 885 patients aged between 25 and 65 years old who visited our ENT and Endocrinology departments. The study was based on biochemical tests, physical examination, hearing assessment, and Pittsburgh Sleep Quality Index test. Statistical analysis used bivariate and multivariate stepwise regression.
Results:
Of 855 hypertensive patients, 184 (21.5%) had hearing loss. There were statistically significant differences between hypertensive patients with and without hearing loss in terms of BMI, smoking, family history of diabetes, tinnitus, vertigo, and headache. Moreover, there were statistically significant differences between hypertensive patients with hearing loss versus those with normal hearing in terms of vitamin D, calcium, magnesium, potassium, fasting glucose, HbA1C, HDL, systolic and diastolic blood pressure, microalbuminuria, and sleep quality. Among hypertensive patients, a multivariate regression analysis (stepwise method) indicated that vertigo, systolic blood pressure, vitamin D deficiency, numbness in the hand, tinnitus, vigorous activity, metabolic syndrome, sleep disturbance, and obesity were all risk predictors of hearing loss.
Conclusions:
Controlling hypertension, vitamin D level, sleep, and lifestyle might lower the risk of hearing loss among hypertensive patients.
REFERENCES (28)
1.
Besser J, Stropahl M, Urry E, Launer S. Comorbidities of hearing loss and the implications of multimorbidity for audiological care. Hear Res, 2018; 369: 3–14.
2.
Bener A, Hanoglu L, Cincik H, Guzel M. Is neuropathy and hypertension associated with increased risk of hearing loss among type 2 diabetic patients? Int J Behav Sci, 2017; 1: 41–6.
3.
Agarwal S, Mishra A, Jagade M, et al. Effects of hypertension on hearing. Indian J Otolaryngol Head Neck Surg, 2013; 65 (Suppl 3): 614–8.
4.
Bener A, Al-Hamaq AOAA, Abdulhadi K, Salahaldin AH, Gonsan L. Interaction between diabetes mellitus and hypertension on risk of hearing loss in highly endogamous population. Diabetes Metab Syndr, 2017; 11 (Suppl 1): S45–S51.
5.
Bener A, Al-Hamaq AOAA, Abdulhadi K, Salahaldin AH, Gansan L. The impact of metabolic syndrome and vitamin D on hearing loss in Qatar. Otolaryngol, 2017; 7(3): 1–6.
6.
de Moraes Marchiori LL, de Almeida Rego Filho E, Matsuo T. Hypertension as a factor associated with hearing loss. Braz J Otorhinolaryngol, 2006; 72: 533–40.
7.
de Moraes Marchiori LL. Tinnitus complaint and blood hypertension in the aging process. Revista Brasileira de Hipertensao, 2009; 16(1): 5–8.
8.
Figueiredo RR, Azevedo AA, Penido NO. Positive association between tinnitus and arterial hypertension. Front Neurol, 2016; 7: 171.
9.
Yang P, Ma W, Zheng Y, Yang H, Lin H. Systematic review and meta-analysis on the association between hypertension and tinnitus. Int J Hypertens, 2015; 2015: 583493.
10.
Jindal M, Hiam L, Raman A, Rejali D et al. Idiopathic intracranial hypertension in otolaryngology. Eur Arch Otorhinolaryngol, 2009; 266(6): 803–6.
11.
Miyata J, Umesawa M, Yoshioka T, Iso H. Association between high systolic blood pressure and objective hearing impairment among Japanese adults: a facility-based retrospective cohort study. Hypertens Res, 2022; 45(1): 155–61.
12.
Bao M, Song Y, Cai J, Wu S, Yang X. Blood pressure variability is associated with hearing and hearing loss: a population-based study in males. Int J Hypertens, 2019; 2018: 9891025.
13.
Bigman G. Deficiency in vitamin D is associated with bilateral hearing impairment and bilateral sensorineural hearing loss in older adults. Nutrition Res, 2022; 105: 1–10.
14.
Dawes P, Cruickshanks KJ, Marsden A, Moore DR, Munro KJ. Relationship between diet, tinnitus, and hearing difficulties. Ear Hear, 2020; 41(2): 289–99.
15.
Holick M, Binkley N, Bischoff-Ferrari H, Gordon CM, Hanley DA, Murad MH, et al. Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab, 2011; 96: 1911–30.
16.
Xie W, Dai Q, Liu J, Liu Y, Hellström S, Duan M. Analysis of clinical and laboratory findings of idiopathic sudden sensorineural hearing loss. Sci Rep, 2020; 10(1): 6057.
17.
Buysse DJ, Reynolds CF, Monk TH, Berman SR, Kupfer DJ. The Pittsburgh Sleep Quality Index: a new instrument for psychiatric practice and research. Psychiatry Res, 1989; 28: 193–213.
18.
Kuang D, Yu YY, Tu C. Bilateral high-frequency hearing loss is associated with elevated blood pressure and increased hypertension risk in occupational noise exposed workers. PLoS One, 2019; 14(9): e0222135.
19.
Rolim LP, Rabelo CM, Lobo IF, Moreiro RR, Samelli AG. Interaction between diabetes mellitus and hypertension on hearing of elderly. Codas, 2015; 27(5): 428–32.
20.
Cruickshanks KJ, Klein R, Klein BE, Wiley TL, Nondahl DM, Tweed TS. Cigarette smoking and hearing loss: the epidemiology of hearing loss study. JAMA, 1998; 279(21): 1715–9.
21.
Wang D, Zhu Y, Li C, Wang Y, Wang S, Wu S, et al. Relationship between cigarette smoking and hearing loss in China: a crosssectional study in Zhejiang province. Tob Induc Dis, 2021; 19: 40.
22.
Syed AH, Hina F, Chandnani A, Kumar V, Kumar J, Garg I, et al. Effect of cigarette smoking on hearing levels in young and middle-aged males. Cureus, 2021 May 18; 13(5): e15093.
23.
Lin BM, Wang M, Stankovic KM, Eavey R, McKenna MJ, Curhan GC, Curhan SG. Cigarette smoking, smoking cessation, and risk of hearing loss in women. Am J Med, 2020; 133(10): 1180–6.
24.
Asplund R. Sleepiness and sleep in elderly subjects with hearing complaints. Arch Gerontol Geriatrics, 2003; 36: 93–9.
25.
Clarke NA, Hoare DJ, Killan EC. Evidence for an association between hearing impairment and disrupted sleep: scoping review. Am J Audiol, 2019; 28(4): 1015–24.
26.
Nakajima K, Kanda E, Hosobuchi A, Suwa K. Subclinical hearing loss, longer sleep duration, and cardiometabolic risk factors in Japanese general population. Int J Otolaryngol, 2014; 2014: 218218.
27.
Szeto B, Valentini C, Lalwani AK. Low vitamin D status is associated with hearing loss in the elderly: a cross-sectional study. Am J Clin Nutr, 2021; 113(2): 456–66.
28.
Toyama K, Mogi M. Hypertension and the development of hearing loss. Hypertens Res, 2022; 45(1): 172–4.
Share
RELATED ARTICLE
We process personal data collected when visiting the website. The function of obtaining information about users and their behavior is carried out by voluntarily entered information in forms and saving cookies in end devices. Data, including cookies, are used to provide services, improve the user experience and to analyze the traffic in accordance with the Privacy policy. Data are also collected and processed by Google Analytics tool (more).
You can change cookies settings in your browser. Restricted use of cookies in the browser configuration may affect some functionalities of the website.
You can change cookies settings in your browser. Restricted use of cookies in the browser configuration may affect some functionalities of the website.
