CASE STUDY
SEVERE DYSARTHRIA DUE TO HYPONATREMIA AND EXTRAPONTINE DEMYELINATION: A SINGLE CASE STUDY
 
More details
Hide details
1
Audiology and Speech language pathology, MERF Institute of Speech and Hearing (p) Ltd, India
 
2
Audiology, All India Institute of Speech and Hearing, India
 
3
Department of Speech Language and Hearing Sciences, Sri Ramachandra Institute of Higher Education and Research, India
 
 
A - Research concept and design; B - Collection and/or assembly of data; C - Data analysis and interpretation; D - Writing the article; E - Critical revision of the article; F - Final approval of article;
 
 
Publication date: 2021-08-31
 
 
Corresponding author
Abishek Umashankar   

Audiology, All India Institute of Speech and Hearing, Manasagangotri, 570009, Mysuru, India
 
 
J Hear Sci 2021;11(2):71-74
 
KEYWORDS
TOPICS
ABSTRACT
Following an unfortunate iatrogenic incident, a 65 year old woman suffered hyponatremia and extrapontine myelinolysis which left her with severe disabilities, including quadriplegia and dysarthria. This case report describes acoustic analysis of her voice, speech, and language which was done using PRAAT software. She had severe dysphonia, and her speech involved slow and inaccurate articulator movements. Hypernasality was observed with an overall reduction in speech intelligibility. Hyperadduction of the true and false vocal cords during voice production was also observed. Speech therapists, as part of a multidisciplinary health team, are of great importance in the functional rehabilitation of such patients.
 
REFERENCES (13)
1.
Adams RD, Victor M, Mancall EL. Central pontine myelinolysis: a hitherto undescribed disease occurring in alcoholic and malnourished patients. AMA Arch Neurol Psychiatry, 1959 Feb; 81(2): 154–72.
 
2.
Martin RJ. Central pontine and extrapontine myelinolysis: the osmotic demyelination syndromes. J Neurol Neurosurg Psychiatry, 2004 Sep; 75(Suppl 3): 22–8.
 
3.
Singh TD, Fugate JE, Rabinstein AA. Central pontine and extrapontine myelinolysis: a systematic review. Eur J Neurol, 2014 Dec; 21(12): 1443–50.
 
4.
Brito AR, Vasconcelos MM, Cruz Júnior LC, Oliveira ME, Azevedo AR, Rocha LG, Mendonça PC. Central pontine and extrapontine myelinolysis: report of a case with a tragic outcome. J Pediatr (Rio J), 2006 Mar-Apr; 82(2): 157–60.
 
5.
Verbalis JG, Goldsmith SR, Greenberg A, Korzelius C, Schrier RW, Sterns RH, Thompson CJ. Diagnosis, evaluation, and treatment of hyponatremia: expert panel recommendations. Am J Med, 2013 Oct; 126(10 Suppl 1): S1–42.
 
6.
Upadhyay A, Jaber BL, Madias NE. Incidence and prevalence of hyponatremia. Am J Med, 2006 Jul; 119(7 Suppl 1): S30–5.
 
7.
Renneboog B, Musch W, Vandemergel X, Manto MU, Decaux G. Mild chronic hyponatremia is associated with falls, unsteadiness, and attention deficits. Am J Med, 2006 Jan; 119(1): 71.
 
8.
Nguyen MK, Ornekian V, Butch AW, Kurtz I. A new method for determining plasma water content: application in pseudohyponatremia. Am J Physiol Renal Physiol, 2007 May; 292(5): F1652–6.
 
9.
McDonald DA. Effects of protein and triglycerides on serum sodium and potassium values obtained by the Kodak dry film potentiometric technique. Can J Med Technol, 1986; 48: 146.
 
10.
Choe WJ, Cho BK, Kim IO, Shin HY, Wang KC. Extrapontine myelinolysis caused by electrolyte imbalance during the management of suprasellar germ cell tumors. Report of two cases. Childs Nerv Syst, 1998 Apr-May; 14(4-5): 155–8.
 
11.
Tsutsumi S, Yasumoto Y, Ito M. Central pontine and extrapontine myelinolysis in an infant associated with the treatment of craniopharyngioma: case report. Neurol Med Chir (Tokyo), 2008 Aug; 48(8): 351–4.
 
12.
Sai Kiran NA, Mohan D, Sadashiva Rao A, Assis ZA, Thakar S, Hegde AS. Reversible extrapyramidal symptoms of extrapontine myelinolysis in a child following surgery for craniopharyngioma. Clin Neurol Neurosurg, 2014 Jan; 116: 96–8.
 
13.
Zhao P, Zong X, Wang X, Zhang Y. Extrapontine myelinolysis of osmotic demyelination syndrome in a case of postoperative suprasellar arachnoid cyst. Case Rep Med, 2012; 2012: 679257.
 
Journals System - logo
Scroll to top